Subject: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026
From: Ruben Calderon <[email-masked]>
To: Rebecca Gritschke <[email-masked]>, Sabine Felloussi <[email-masked]>
Cc: Guillermo Lopez <[email-masked]>, Luis Henriquez <[email-masked]>, Hillmer Vallenilla <[email-masked]>, Annette Angulo <[email-masked]>, Trademarks Bolet & Terrero <[email-masked]>, Paula Alfaro <[email-masked]>
Date: Tue, 19 May 2026 16:11:03 +0000

Dear Rebecca,

We confirm we have filed the response to the cancellation action.

We look forward to receiving further comments and instructions regarding additional evidence and a possible defensive application.

Best regards,

De: Ruben Calderon
Enviado el: lunes, 18 de mayo de 2026 11:03 a. m.
Para: 'Rebecca Gritschke' <[email-masked]>; Sabine Felloussi <[email-masked]>
CC: Guillermo Lopez <[email-masked]>; Luis Henriquez <[email-masked]>; Hillmer Vallenilla <[email-masked]>; Annette Angulo <[email-masked]>; Trademarks Bolet & Terrero <[email-masked]>; Paula Alfaro <[email-masked]>
Asunto: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Rebecca,

Thanks for your prompt response.

We will file the response with the available materials covering uses from 2025 and 2026.

Once we receive further evidence, we may file it through a complimentary brief.

We also look forward to receiving your comments on the defensive application.

Best regards,

De: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
Enviado el: lunes, 18 de mayo de 2026 11:01 a. m.
Para: Ruben Calderon <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
CC: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Asunto: AW: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Ruben,

Thank you very much for your kind reminder but I have to regret that we have not received further materials from our business. Please let me know how we can proceed in this case.

Kind regards,

Rebecca

Rebecca Gritschke
Trademark Paralegal
Cardiovascular, Metabolism & Endocrinology
Group Legal & Compliance/ Trademarks EF-LE-TA

Merck

Merck KGaA | Frankfurter Str. 250 | Postcode: A003/909 | 64293 Darmstadt | Germany
Phone: +49 6151 72 7294 | Fax: +49 6151 72 3378
E-mail: [email-masked]<mailto:[email-masked]> | www.merckgroup.com<http://www.merckgroup.com/>
Mandatory information can be found at: http://www.merckgroup.com/mandatories
Pflichtangaben finden Sie unter: http://www.merckgroup.com/mandatories

Check out our new EVA page!<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

Von: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Gesendet: Montag, 18. Mai 2026 15:17
An: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Betreff: Re: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Urgent reminder

[firma rdc.png]

From: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Date: Thursday, May 14, 2026 at 10:15 AM
To: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Subject: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026
Dear Rebecca,

We thank you for the provided report.

This will be very helpful. However, under recent criteria of the VPTO, it will not be sufficient as it covers a time period different than 2021-2023.

In that regard, may you kindly clarify and provide the following if the information is available:

  *   Please provide the regulatory approvals listed in the report (E.F. 31.687/23 and E.F. 31.686/23). When were these approvals filed and decided?
  *   We understand that due to business decisions, the relaunch of the CONCOR mark began in 2025. We also note from the report that several marketing and launch activities occurred in alliance with DOLLY PHARMA. May you further develop on the relationship between MERCK and DOLLY PHARMA? Would you be able to provide documents (preferably signed between 2021-2023) detailing this commercial relationship and its intent to commercialize CONCOR products?
  *   In recent decisions, the VPTO has analyzed force majeure arguments in the context of cancellation actions (for instance, impossibility to market products due to regulatory burdens during the pandemic). Is there any indication on MERCK’s records that would allow us to prove that the unavailability of CONCOR in Venezuela was caused by a force majeure event?

Finally, considering the available we have received so far, we highly encourage filing a defensive application for the mark CONCOR in class 5. Considering there are no restrictions to file an identical application, filing a fresh application will allow MERCK to have a pending application while the cancellation is being decided. Kindly let us know if this is a viable approach so we may provide a cost estimate.

Best regards,

De: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
Enviado el: miércoles, 13 de mayo de 2026 4:47 a. m.
Para: Ruben Calderon <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
CC: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Asunto: AW: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Ruben,

Thank you very much for your email. Attached you will find use material provided by our business. Please let me know if this is sufficient. We have asked our business to provide us with more evidence especially for the years 2021 – 2023. As soon as we shall receive it I shall forward it to you immediately.

Kind regards,

Rebecca

Rebecca Gritschke
Trademark Paralegal
Cardiovascular, Metabolism & Endocrinology
Group Legal & Compliance/ Trademarks EF-LE-TA

Merck

Merck KGaA | Frankfurter Str. 250 | Postcode: A003/909 | 64293 Darmstadt | Germany
Phone: +49 6151 72 7294 | Fax: +49 6151 72 3378
E-mail: [email-masked]<mailto:[email-masked]> | www.merckgroup.com<http://www.merckgroup.com/>
Mandatory information can be found at: http://www.merckgroup.com/mandatories
Pflichtangaben finden Sie unter: http://www.merckgroup.com/mandatories

Check out our new EVA page!<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

Von: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Gesendet: Freitag, 8. Mai 2026 19:09
An: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Betreff: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Rebecca,

We thank you for your email. We look forward to receiving the business materials from CONCOR.

Regarding the provided websites, please note that under the current criteria of the VPTO, we require the evidence to precisely showcase the date of the use during the relevant period (i.e. between 2021 and 2023). For instance, if possible, we would require Archived websites alongside invoices or receipts issued during the relevant period.

We look forward to receiving your comments.

Best regards,

De: Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
Enviado el: lunes, 4 de mayo de 2026 7:13 a. m.
Para: Ruben Calderon <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
CC: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Asunto: AW: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Rubén,

I refer to your email below. We have asked the business to obtain user materials for prove the use of our trademark CONCOR in Venezuela. As soon as we shall have received the documents we shall forward them to you.

We have made a quick online check regarding the use of CONCOR in Venezuela and have found the following websites showing the sale of CONCOR.

Concor 2,5mg 30tabletas Bisoprolol Merck<https://urldefense.com/v3/__https:/www.farmatodo.com.ve/producto/116159523-concor-25mg-30tabletas-bisoprolol-merck?wpsrc=Organic*Search&wpsn=www.bing.com__;Kw!!Eu8ikxSnpXkBCg!a5hD1PC2kDHr_9FBCBWsinD5iQFgofhn_SKN7D53ATlRFrQxUNOw8c7Zli7EQ34oVybAQJlP0WdlOsQJX8n2ri_jGAfH6w$>

Concor Bisoprolol 2.5Mg X 30 Tabletas Merck - Farmadon - La Farmacia de la Esquina<https://urldefense.com/v3/__https:/www.farmadon.com.ve/producto/concor-bisoprolol-2-5mg-x-30-tabletas-merck/__;!!Eu8ikxSnpXkBCg!a5hD1PC2kDHr_9FBCBWsinD5iQFgofhn_SKN7D53ATlRFrQxUNOw8c7Zli7EQ34oVybAQJlP0WdlOsQJX8n2ri_XS2KPuA$>

CONCOR 5MG X 30 TAB (BISOPROLOL)(MERCK) – Farmapaz-Venezuela<https://urldefense.com/v3/__https:/farmapazvenezuela.com/product/concor-5mg-x-30-tab-bisoprolol-merck/?v=5f02f0889301__;!!Eu8ikxSnpXkBCg!a5hD1PC2kDHr_9FBCBWsinD5iQFgofhn_SKN7D53ATlRFrQxUNOw8c7Zli7EQ34oVybAQJlP0WdlOsQJX8n2ri8jjhxa6Q$>

Please let us know if these website founds are also sufficient.

Kind regards,

Rebecca

Rebecca Gritschke
Trademark Paralegal
Cardiovascular, Metabolism & Endocrinology
Group Legal & Compliance/ Trademarks EF-LE-TA

Merck

Merck KGaA | Frankfurter Str. 250 | Postcode: A003/909 | 64293 Darmstadt | Germany
Phone: +49 6151 72 7294 | Fax: +49 6151 72 3378
E-mail: [email-masked]<mailto:[email-masked]> | www.merckgroup.com<http://www.merckgroup.com/>
Mandatory information can be found at: http://www.merckgroup.com/mandatories
Pflichtangaben finden Sie unter: http://www.merckgroup.com/mandatories

Check out our new EVA page!<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

<https://evarooms.merckgroup.com/Topic/LE-T/Pages/Trademarks-Home.aspx>

Von: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Gesendet: Freitag, 24. April 2026 16:38
An: Sabine Felloussi <[email-masked]<mailto:[email-masked]>>; Jessica Schmidt <[email-masked]<mailto:[email-masked]>>; Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Betreff: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Sabine,

We thank you for your information, it is very helpful.

Please note that, under Venezuelan law, the relevant period of use is two years prior to the filing of the cancellation action. In this case, the cancellation was filed on January 20, 2023. Therefore, the evidence must prove the use of the mark between January 20, 2021 and January 20, 2023. Was the Concord mark used during this period?

We note from your report that the mark was used since 2025. This evidence is still helpful and relevant despite covering a different period. Hence, please provide sales figures, invoices and any other data available.

Regarding the list of goods, the VPTO has not recently issued decisions on partial cancellations. Instead, the VPTO generally evaluates the use of the mark in at least one of the products listed in the specification.

We look forward to receiving your comments.

Best regards,

De: Sabine Felloussi <[email-masked]<mailto:[email-masked]>>
Enviado el: viernes, 17 de abril de 2026 5:41 a. m.
Para: Ruben Calderon <[email-masked]<mailto:[email-masked]>>; Jessica Schmidt <[email-masked]<mailto:[email-masked]>>; Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
CC: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Asunto: AW: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Ruben,

I refer to your attached Email.

Yes, we need to maintain the mark in Venezuela. We have started to use the mark CONCOR in Venezuela last year (sales around 120 TUSD)

Rebecca has contacted the local business for evidence of use and she will forward the documents to you asap.

Regarding the lists of goods, our mark is registered for “pharmaceutical, veterinary and sanitary preparations”, but is used for beta blocking agents. We are happy to delete “veterinary and sanitary preparations” from our list of goods if this is helpful in this case.

Looking forward to hearing from you.

Kind regards,
Sabine

Sabine Felloussi

Trademark Counsel
EF-LE-TA Healthcare, CM & E
Group Legal & Compliance | Trademarks, Designs & Copyright

Merck KGaA | Frankfurter Str. 250 | Postcode: F128/002 | 64293 Darmstadt | Germany
Phone: +49 6151 72 9395 | Fax: +49 6151 72 3378 | E-mail: [email-masked]<mailto:[email-masked]>
www.merckgroup.com<http://www.merckgroup.com/>

Mandatory information can be found at: http://www.merckgroup.com/mandatories
Pflichtangaben finden Sie unter: http://www.merckgroup.com/mandatories

Von: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Gesendet: Donnerstag, 16. April 2026 22:57
An: Jessica Schmidt <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>; Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Betreff: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear colleagues,

Please find attached the cancellation brief.

From our review of the brief, the cancellation was filed by Mr. Shum Ronghui. Mr Ronghui applied for the trademark CONCORD in class 5 (App. No. 2022-003413) to identify “SANITARY PADS, TAMPONS, AND PANTI LINERS; HYGIENE AND SANITARY PRODUCTS FOR MEDICAL USE; BABY DIAPERS AND
INCONTINENCE PRODUCTS”.

The CONCORD application was Ex-Officio rejected by the VPTO on the basis of Merck’s CONCOR registration. Consequently, Mr. Ronghui appealed the rejection and filed the cancellation action.

Please note that, under Venezuela’s cancellation procedure, the burden of proof on the use of the mark falls on the trademark owner. Therefore, we look forward to receiving your comments regarding interest and use of the mark so we may provide a detailed analysis.

Best regards,

De: Jessica Schmidt <[email-masked]<mailto:[email-masked]>>
Enviado el: miércoles, 15 de abril de 2026 1:25 a. m.
Para: Ruben Calderon <[email-masked]<mailto:[email-masked]>>; Sabine Felloussi <[email-masked]<mailto:[email-masked]>>; Rebecca Gritschke <[email-masked]<mailto:[email-masked]>>
CC: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Asunto: RE: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Rubén,

Thank you for your message.

I’ve included my colleagues Sabine and Rebecca in this email, as they take care of trademark CONCOR.

Dear Sabine and Rebecca,

Please see the email below.

Best regards,
Jessica

Jessica Schmidt, LL.M.
Senior Corporate Counsel
Head of Team Healthcare (EF-LE-TA)
Group Legal & Compliance / Trademarks, Designs & Copyright

Merck

Merck KGaA | Frankfurter Str. 250 | Postcode: A003/909| 64293 Darmstadt | Germany
Phone: +49 6151 72 6800 | E-mail: [email-masked]<mailto:[email-masked]>
www.merckgroup.com<http://www.merckgroup.com/>

Mandatory information can be found at: http://www.merckgroup.com/mandatories
Pflichtangaben finden Sie unter: http://www.merckgroup.com/mandatories

From: Ruben Calderon <[email-masked]<mailto:[email-masked]>>
Sent: Mittwoch, 15. April 2026 01:51
To: Jessica Schmidt <[email-masked]<mailto:[email-masked]>>
Cc: Guillermo Lopez <[email-masked]<mailto:[email-masked]>>; Luis Henriquez <[email-masked]<mailto:[email-masked]>>; Hillmer Vallenilla <[email-masked]<mailto:[email-masked]>>; Annette Angulo <[email-masked]<mailto:[email-masked]>>; Trademarks Bolet & Terrero <[email-masked]<mailto:[email-masked]>>; Paula Alfaro <[email-masked]<mailto:[email-masked]>>
Subject: Venezuela - Cancellation Action against trademark CONCOR - Deadline: May 18, 2026

Dear Jessica,
We hope this message finds you well.
In the current Official Bulletin No. 652, we were notified of a Cancellation Action for Non-Use filed against MERCK KGAA’s registration for the trademark CONCOR in class 5, Registration No. P231946
We have requested the case file from the Trademark Office to review the cancellation brief. As soon as we have it, we will send you a copy through this channel.
Cancellation actions are governed by a new procedure that grants the owner a period of ten (10) days to review the brief, and after this period, fifteen (15) days to submit arguments and evidence of use. Consequently, the deadline to file the response expires on May 18, 2026.
Given the short response time under this new procedure, we would appreciate your comments on the following points:
•                Interest in the trademark: Do you wish to maintain the CONCOR registration?
•                Use of the trademark: Has the trademark been used recently in Venezuela? if there any evidence of use?
This information will help us define the best strategy, assess the chances of success, and estimate possible costs.
If there is no evidence of use, the chances of obtaining a favorable decision are, in principle, low. In any case, we remain attentive to your comments to continue evaluating the matter.
Best regards,

This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith.

Click merckgroup.com/disclaimer<https://www.merckgroup.com/en/legal-disclaimer/mail-disclaimer.html> to access the German, French, Spanish, Portuguese, Turkish, Polish and Slovak versions of this disclaimer.

Please find our Privacy Statement information by clicking here: merckgroup.com/privacy-statements-by-location<https://www.merckgroup.com/en/privacy-statement/privacy-statements-by-location.html>

This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith.

Click merckgroup.com/disclaimer<https://www.merckgroup.com/en/legal-disclaimer/mail-disclaimer.html> to access the German, French, Spanish, Portuguese, Turkish, Polish and Slovak versions of this disclaimer.

Please find our Privacy Statement information by clicking here: merckgroup.com/privacy-statements-by-location<https://www.merckgroup.com/en/privacy-statement/privacy-statements-by-location.html>

This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith.

Click merckgroup.com/disclaimer<https://www.merckgroup.com/en/legal-disclaimer/mail-disclaimer.html> to access the German, French, Spanish, Portuguese, Turkish, Polish and Slovak versions of this disclaimer.

Please find our Privacy Statement information by clicking here: merckgroup.com/privacy-statements-by-location<https://www.merckgroup.com/en/privacy-statement/privacy-statements-by-location.html>

This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith.

Click merckgroup.com/disclaimer<https://www.merckgroup.com/en/legal-disclaimer/mail-disclaimer.html> to access the German, French, Spanish, Portuguese, Turkish, Polish and Slovak versions of this disclaimer.

Please find our Privacy Statement information by clicking here: merckgroup.com/privacy-statements-by-location<https://www.merckgroup.com/en/privacy-statement/privacy-statements-by-location.html>

This message and any attachment are confidential and may be privileged or otherwise protected from disclosure. If you are not the intended recipient, you must not copy this message or attachment or disclose the contents to any other person. If you have received this transmission in error, please notify the sender immediately and delete the message and any attachment from your system. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not accept liability for any omissions or errors in this message which may arise as a result of E-Mail-transmission or for damages resulting from any unauthorized changes of the content of this message and any attachment thereto. Merck KGaA, Darmstadt, Germany and any of its subsidiaries do not guarantee that this message is free of viruses and does not accept liability for any damages caused by any virus transmitted therewith.

Click merckgroup.com/disclaimer<https://www.merckgroup.com/en/legal-disclaimer/mail-disclaimer.html> to access the German, French, Spanish, Portuguese, Turkish, Polish and Slovak versions of this disclaimer.

Please find our Privacy Statement information by clicking here: merckgroup.com/privacy-statements-by-location<https://www.merckgroup.com/en/privacy-statement/privacy-statements-by-location.html>